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notes biology science

Cephalic furrow preLights

preLights is a (another) great initiative from The Company of Biologists where teams of scientists review and comment on preprints of interest for the biology community. I was delighted to hear that they were going to highlight our cephalic furrow preprint (Vellutini et al.) combined with the cephalic furrow preprint of Lemke and Wang labs […]

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biology articles imaging

Cephalic furrow thread

I published a cephalic furrow thread about our paper on Twitter and Mastodon. We recently updated the manuscript on bioRxiv. In addition to the tissue mechanics, this new version includes gene expression data comparing Drosophila with Clogmia, a fly that has no cephalic furrow… It gives us some hints about the patterning changes associated with […]

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notes biology

Cephalic furrow on bioRxiv

Our paper about the function of the cephalic furrow in the fruit fly is ready and now available as a preprint in bioRxiv! To access: https://doi.org/10.1101/2023.03.30.534554 P. S. Apart from the poem The Great Divide, I didn’t write much about the cephalic furrow here. But this will change.

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notes science

Introduction to Science Mastodon

After a first try back in 2020, I’ve recently migrated my account to my new social handle (@bruvellu) and started using Mastodon again. I’m excited about it. Migrating away from Twitter (and other corporate social silos) will be good for the web in general and for science communities in particular. Here’s my introduction to the […]

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biology articles imaging

Mitotic waves and gastrulation in a fly embryo

Last year I published a snapshot of a mitotic wave in a fruit fly embryo. Here’s the video of that same embryo going through cleavage (nuclei divisions) and gastrulation (cell movements): Mitotic waves What you see at the beginning of the movie are the cycles of synchronous nuclei divisions. They happen in waves from the […]

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notes biology

Mechanobiology conference

Mechanobiology investigates the role of physical forces in embryonic development. This week, the conference Mechanobiology in development and disease is happening in the EMBL Heidelberg. I’ll present my work on how the fold that divides the head from the trunk in Drosophila embryos—the cephalic furrow—may have an important mechanical role for gastrulation.

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biology notes

The Great Divide

Cephalic furrow the early foldDivides the embryo in one go.Pulling in on its ownDeep it sinks into the yolk. This great divide of tissue foldSplits the embryo in back and front.But why the furrow once it growsStretches flat and gone it goes? A fold that folds and then unfoldsLeave us wondering what’s the role.

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imaging biology notes

A mitotic wave

A mitotic wave traveling through an early #Drosophila #embryo #FlyFriday

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imaging articles code

ImageJ macro to synchronize and combine image stacks

When I film embryos under the microscope, some will be younger and some will be older than others—they are never in perfect synchrony. This is fine when watching the recordings of individual embryos, but becomes an issue when you want to watch two (or more) embryos developing side-by-side. In my case, I want to identify […]

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science notes

Fly Station

Fly Station is ready for the #LNdWDD @mpicbg