I published a cephalic furrow thread about our paper on Twitter and Mastodon. We recently updated the manuscript on bioRxiv. In addition to the tissue mechanics, this new version includes gene expression data comparing Drosophila with Clogmia, a fly that has no cephalic furrow… It gives us some hints about the patterning changes associated with […]
Our paper about the function of the cephalic furrow in the fruit fly is ready and now available as a preprint in bioRxiv! To access: https://doi.org/10.1101/2023.03.30.534554 P. S. Apart from the poem The Great Divide, I didn’t write much about the cephalic furrow here. But this will change.
After a first try back in 2020, I’ve recently migrated my account to my new social handle (@bruvellu) and started using Mastodon again. I’m excited about it. Migrating away from Twitter (and other corporate social silos) will be good for the web in general and for science communities in particular. Here’s my introduction to the […]
Mechanobiology investigates the role of physical forces in embryonic development. This week, the conference Mechanobiology in development and disease is happening in the EMBL Heidelberg. I’ll present my work on how the fold that divides the head from the trunk in Drosophila embryos—the cephalic furrow—may have an important mechanical role for gastrulation.
Cephalic furrow the early foldDivides the embryo in one go.Pulling in on its ownDeep it sinks into the yolk. This great divide of tissue foldSplits the embryo in back and front.But why the furrow once it growsStretches flat and gone it goes? A fold that folds and then unfoldsLeave us wondering what’s the role.